Dr. Augustine Choi is Chairman of Medicine at Weill Cornell Medical College, Physician-in-Chief at New York-Presbyterian/Weill Cornell Medical Center, and a world-renowned expert of Chronic Obstructive Lung Disease (COPD). In a conversation with Dr. Maor Sauler, Dr. Choi reviews the evolution of our understanding of COPD, highlighting recent advances and changing concepts. He also discusses his own seminal contributions to the field of COPD biology, conjectures about the future of COPD research, and gives advice to trainees and junior investigators. Don’t miss this exciting opportunity to hear from one of today's leaders of pulmonary medicine.
Presenter DisclosuresAugustine Choi: No relevant commercial interests.
Maor Sauler: No relevant commercial interests.
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References:
Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice. Cloonan SM, Glass K, Laucho-Contreras ME, Bhashyam AR, Cervo M, Pabón MA, Konrad C, Polverino F, Siempos II, Perez E, Mizumura K, Ghosh MC, Parameswaran H, Williams NC, Rooney KT, Chen ZH, Goldklang MP, Yuan GC, Moore SC, Demeo DL, Rouault TA, D'Armiento JM, Schon EA, Manfredi G, Quackenbush J, Mahmood A, Silverman EK, Owen CA, Choi AM. Nat Med. 2016 Feb;22(2):163-74. doi: 10.1038/nm.4021. Epub 2016 Jan 11. PMID: 26752519
Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD.Mizumura K, Cloonan SM, Nakahira K, Bhashyam AR, Cervo M, Kitada T, Glass K, Owen CA, Mahmood A, Washko GR, Hashimoto S, Ryter SW, Choi AM. J Clin Invest. 2014 Sep;124(9):3987-4003. doi: 10.1172/JCI74985. Epub 2014 Aug 1.PMID: 25083992
Autophagy in pulmonary diseases. Ryter SW, Nakahira K, Haspel JA, Choi AM. Annu Rev Physiol. 2012;74:377-401. doi: 10.1146/annurev-physiol-020911-153348. Epub 2011 Oct 24. Review. PMID: 22035347
