In this “Breathe Easy Critical Perspective” podcast, Dr. Dominique Pepper interviews Dr. Michael Pinsky. They discuss heart-lung interactions, functional hemodynamics, machine learning, and Dr. Pinsky's career path over the last 4 decades. Dr. Pinsky is the recipient of the 2020 ATS Assembly of Critical Care Lifetime Achievement Award. Dr. Pinsky is also a Professor of Critical Care Medicine, Bioengineering, Cardiovascular Diseases, Anesthesiology & Clinical & Translational Diseases at the University of Pittsburgh, Pennsylvania.