Reviewed By Allergy, Immunology & Inflammation Assembly
Submitted by
Jonathan P. Parsons, M.D.
Assistant Professor of Internal Medicine
The Ohio State University Medical Center
Columbus, Ohio
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History
An 18 year-old female college student presents to the student health center complaining of cough and chest tightness that occurs frequently with exercise. She is on the varsity field-hockey team and notes she occasionally has trouble keeping up with the other players during practice and games. Her coach has been criticizing her frequently for what he construes as “poor effort.” Her cough is episodic and is non-productive. Her dyspnea seems to occur after several minutes of exercise, and she states it feels like she cannot get a deep breath. She does not notice symptoms at other times of the day when she is not exercising. She has been particularly stressed emotionally recently as her first final exam period in college is approaching, and her field-hockey team has advanced to the semifinals of the conference tournament. Her review of symptoms is otherwise unremarkable.
Her past medical history is only significant for a torn knee ligament two years prior to her current presentation. She has no known history of asthma and does not have problems with perennial allergies. She takes oral contraceptive pills and nutritional supplements and denies any known drug allergies. She is a freshman in college and does not smoke. She admits to alcohol use in moderation and denies any illicit drug use. Her family medical history is unremarkable; her sister and parents are healthy without significant medical problems including asthma.
Physical Exam
Lab
Spirometry: FVC of 104% of predicted, FEV1 of 98% of predicted, normal FEV1/FVC ratio, and normal flow-volume loops.
Electrocardiogram: Normal sinus rhythm, normal intervals, and no ST-segment changes.
Eucapnic voluntary hyperventilation testing: 13% drop in FEV1 compared to baseline documented at 10 minutes post-test.
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